Chelsea Handler has branded Angelina Jolie "insincere".

The 'Chelsea Lately' host - who branded the 'Tourist' star a "homewrecker" last week - has again hit out at the actress, admitting she wouldn't want to spend time in her company.

Chelsea - a close friend of Jennifer Aniston, the ex-wife of Angelina's partner Brad Pitt - said: "I'm not a fan. She just doesn't come off to me as a sincere woman. She seems like a woman that you'd really want to avoid."

While Chelsea has nothing good to say about Angelina, she was full of praise for her friend Jennifer.

She told America's Glamour magazine: "Jennifer Aniston makes me laugh. She sends me really, really funny emails. She's hilarious and irreverent."

Though the comic was criticised for her foul-mouthed tirade against Angelina - in which she also branded her a "f***ing ****" - on stage last week, the 35-year-old star insists she has some limits when it comes to writing her jokes.

She explained: "I think talking about children and their looks is not nice. Like, unattractive children. I don't do that. And I don't talk about people who are dying. I think that's inappropriate."