Vixen guitarist Jan Kuehnemund has lost her cancer battle at the age of 51.

The girl group founder and lead guitarist passed away on Thursday (10Oct13), according to reports.

The Minnesota native formed Vixen in high school and moved the band to Los Angeles in the mid-1980s, later signing to Emi and releasing a self-titled debut album in 1988.

Vixen also hit the singles charts with Cryin' and Edge of a Broken Heart, and the bandmates appeared in director Penelope Spheeris' film The Decline of Western Civilization Ii: The Metal Years.

Regulars on MTV, the group followed up their debut album with Rev It Up in 1990.

Kuehnemund briefly reunited the band's classic line-up for Vh1's Bands Reunited in 2004.