Former Divinyls frontwoman Chrissy Amphlett has died at the age of 53.

The Australian singer passed away at her home in New York City on Sunday (21Apr13) with her husband, former Divinyls drummer Charley Drayton, by her side.

Amphlett revealed she was living with multiple sclerosis in 2007, and in 2010, she was dealt another blow when doctors diagnosed her with breast cancer.

Drayton says in a statement, "Christine Joy Amphlett succumbed to the effects of breast cancer and multiple sclerosis, diseases she vigorously fought with exceptional bravery and dignity. She passed gently, in her sleep, surrounded by close friends and family... Chrissy's light burns so very brightly. Hers was a life of passion and creativity; she always lived it to the fullest. With her force of character and vocal strength she paved the way for strong, sexy, outspoken women."