Veteran newsman Tom Brokaw, who wrote the book Where Were You? America Remembers the JFK Assassination, sat down with celebrities, politicians and dignitaries to discuss the day President Kennedy died - and their memories of it.
Fonda said, "It just seemed impossible that this great president... was dead. It's like everything became unsafe... It shook my world view."
The news special will air on Friday night (22Nov13) in America.
The mystery surrounding Kennedy's death remains but it is believed he was killed when gunman Lee Harvey Oswald opened fire on the presidential motorcade as it weaved through Dallas, Texas.
A moment of silence following the tolling of bells in Dallas as part of ceremonies to honour President Kennedy on the 50th anniversary of his assassination was staged on Friday morning at 11.30am local time.